Dr. ir. R. Wierts

Roel Wierts heeft technische natuurkunde gestudeerd aan de Technische Universiteit Eindhoven. Na het behalen van zijn Master met vermelding cum laude, heeft hij de opleiding tot klinisch fysicus gevolgd in het universitair medisch centrum in Groningen.

Sinds 2011 werkt hij als geregistreerd klinisch fysicus op de afdeling Beeldvorming van het Maastricht universitair medisch centrum+ (MUMC+) met als aandachtsgebied nucleaire geneeskunde. Tevens is hij coördinerend stralingsdeskundige en lid van de opleidingsgroep klinisch fysica van het MUMC+. In mei 2018 is hij gepromoveerd met als onderwerp "Tailored dosimetry in the radioiodine treatment of differentiated thyroid cancer".

Publicaties

Peters SMB, van der Werf NR, Segbers M, van Velden FHP, Wierts R, Blokland KJAK, Konijnenberg MW, Lazarenko SV, Visser EP, Gotthardt M, Towards standardization of absolute SPECT/CT quantification: a multi-center and multi-vendor phantom study. EJNMMI Phys, 2019. 6(1):29

Boswijk E, Franssen R, Vijgen GHEJ, Wierts R, van der Pol JAJ, Mingels AMA, Cornips EMJ, Majoie MHJM, van Marken Lichtenbelt WD, Mottaghy FM, Wildberger JE, Bucerius J, Short-term discontinuation of vagal nerve stimulation alters 18F-FDG blood pool activity: an exploratory interventional study in epilepsy patients. EJNMMI Res, 2019. 9(1):101

Peerlings J, Paulis L, Mitea C, Bakers F, Berbée M, Wierts R, Vöö S, Wildberger J, Hoffmann A, Lambin P, Mottaghy F, Performing clinical 18F-FDG-PET/MRI of the mediastinum optimising a dedicated, patient-friendly protocol, Nucl Med Commun, 2019. 40(8):815-826

Bauwens M, Pooters I, Cobben R, Visser M, Schnerr R, Mottaghy F, Wildberger J, Wierts R, A comparison of four radionuclide dose calibrators using various radionuclides and measurement geometries clinically used in nuclear medicine. Phys Med, 2019. 60: p. 14-21.

Boswijk E, Sanders KJC, Broeders EPM, de Ligt M, Vijgen GHEJ, Havekes B, Mingels AMA, Wierts R, van Marken Lichtenbelt WD, Schrauwen P, Mottaghy FM, Wildberger JE, Bucerius J, TSH suppression aggravates arterial inflammation – an 18F-FDG PET study in thyroid carcinoma patients. Eur J Nucl Med Mol Imaging, 2019. 46(7): p. 1428-1438.

Wierts R, Conti M, Claessen AGG, Herrmann K, Kemerink GJ, Binse I, Wildberger JE, Mottaghy FM, Backes WH, Jentzen W, Impact of prompt gamma coincidence correction on absorbed dose estimation in differentiated thyroid cancer using 124I PET/CT imaging. Nucl Med Commun, 2018. 39(12): p. 1156-1164.

Van Lierop ZYGJ, Jentjens S, Anten MHME, Wierts R, Stumpel CT, Havekes B, van Kroonenburgh MJPG, Thyroid gland 18F-FDG uptake in neurofibromatosis type 1. Eur Thyroid J, 2018. 7(3): p. 155-161.

Wierts R, Jentzen W, Quick HH, Wisselink HJ, Pooters INA, Wildberger JE, Herrmann K, Kemerink GJ, Backes WH, Mottaghy FM, Quantitative performance evaluation of 124I PET/MRI lesion dosimetry in differentiated thyroid cancer. Phys Med Biol, 2017. 63(1)

Schnerr RS, de Jong AN, Landry G, Jeukens CR, Wierts R, Monte Carlo simulations of ceiling scatter in nuclear medicine: 99mTc, 131I and 18F. Med Phys, 2017. 44(3): p. 1113-1119.

Verwer EE, Zegers CM, van Elmpt W, Wierts R, Windhorst AD, Mottaghy FM, Lambin P, Boellaard R, Pharmacokinetic modelling of a novel hypoxia PET tracer [18F] HX4 in patients with non-small cell lung cancer. EJNMMI Phys, 2016. 3(1): 30.

Jentzen W, Verschure F, van Zon A, van de Kolk R, Wierts R, Schmitz J, Bockisch A, Binse I, 124I PET assessment of response of bone metastases to initial radioiodine treatment of differentiated thyroid cancer. J Nucl Med, 2016. 57(10): p. 1499-1504.

Vöö S, Kwee RM, Sluimer JC, Schreuder FH, Wierts R, Bauwens M, Heeneman S, Cleutjens JP, van Oostenbrugge RJ, Daemen JW, Daemen MJ, Mottaghy FM, Kooi ME, Imaging intraplaque inflammation in carotid atherosclerosis with 18F-fluorocholine positron emission tomography-computed tomography: perspective study on vulnerable atheroma with immunohistochemical validation. Circ Cardiovasc Imaging, 2016. 9(5).

Hendrikx G, Bauwens M, Wierts R, Mottaghy FM, Post MJ, Left ventricular function measurements in a mouse myocardial infarction model. Comparison between 3D-echocardiography and ECG-gated SPECT. Nuklearmedizin, 2016. 55(3): p. 115-122.

Wierts R, Brans B, Havekes B, Kemerink GJ, Halders SG, Schaper NN, Backes WH, Mottaghy FM, Jentzen W, Dose-response relationship in differentiated thyroid cancer patients undergoing radioiodine treatment assessed by means of 124I PET/CT. J Nucl Med, 2016. 57(7): p. 1027-1032.

Peters M, Willems P, Weijers R, Wierts R, Jutten L, Urbach C, Arts C, van Rhijn L, Brans B, Pseudarthrosis after lumbar spinal fusion: the role of 18F-fluoride PET/CT. Eur J Nucl Med Mol Imaging, 2015. 42(12): p. 1891-1898.

Peters MJ*, Wierts R*, Jutten EM, Halders SG, Willems PC, Brans B, Evaluation of a short dynamic 18F-fluoride PET/CT scanning method to assess bone metabolic activity in spinal orthopedics. Ann Nucl Med, 2015. 29(9): p. 799-809. * Both authors contributed equally

Hendrikx G, De Saint-Hubert M, Dijkgraaf I, Bauwens M, Douma K, Wierts R, Pooters I, van den Akker NM, Hackeng TM, Post MJ, Mottaghy FM, Molecular imaging of angiogenesis after myocardial infarction by (111)In-DTPA-cNGR and (99m)Tc-sestamibi dual-isotope myocardial SPECT. EJNMMI Res, 2015. 5:2.

Hanssen MJ, Wierts R, Hoeks J, Gemmink A, Brans B, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD, Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance. Diabetologia, 2015. 58(3): p. 586-595.

van der Lans AA, Wierts R, Vosselman MJ, Schrauwen P, Brans B, van Marken Lichtenbelt WD, Cold-activated brown adipose tissue in human adults: methodological issues. Am J Physiol Regul Integr Comp Physiol, 2014. 307(2): p. R103-113.

Bauwens M, Wierts R, van Royen B, Bucerius J, Backes W, Mottaghy F, Brans B, Molecular imaging of brown adipose tissue in health and disease. Eur J Nucl Med Mol Imaging, 2014. 41(4): p. 776-791.

Makris NE, Boellaard R, Visser EP, de Jong JR, Vanderlinden B, Wierts R, van der Veen BJ, Greuter HJ, Vugts DJ, van Dongen GA, Lammertsma AA, Huisman MC, Multicenter harmonization of 89Zr PET/CT performance. J Nucl Med, 2014. 55(2): p. 264-267.

Zegers CM, van Elmpt W, Wierts R, Reymen B, Sharifi H, Öllers MC, Hoebers F, Troost EG, Wanders R, van Baardwijk A, Brans B, Eriksson J, Windhorst B, Mottaghy FM, De Ruysscher D, Lambin P, Hypoxia imaging with [18F]HX4 in NSCLC patients: defining optimal imaging parameters. Radiother Oncol, 2013. 109(1): p. 58-64.

Vosselman MJ, Bran B, van der Lans AA, Wierts R, van Baak MA, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD, Brown adipose tissue activity after a high-calorie meal in humans. Am J Clin Nutr, 2013. 98(1): p. 57-64.

Vosselman MJ, van der Lans AA, Brans B, Wierts R, van Baak MA, Schrauwen P, van Marken Lichtenbelt WD, Systemic -adrenergic stimulation of thermogenesis is not accompanied by brown adipose tissue activity in humans. Diabetes, 2012. 61(12): p. 3106-3113.

Brans B, Weijers R, Halders S, Wierts R, Peters M, Punt I, Willems P, Assessment of bone graft incorporation by 18 F-fluoride positron-emission tomography/computed tomography in patients with persisting symptoms after posterior lumbar interbody fusion. EJNMMI Res, 2012. 2(1): 42.

Wierts R, de Pont CD, Brans B, Mottaghy FM, Kemerink GJ, Dosimetry in molecular nuclear therapy. Methods, 2011. 55(3): p. 196-202.

Wierts R, de Jong JR, Lazarenko SV, Paans AM, Dierckx RA, Characteristics of a new system for monitoring the leakage factor during regional hyperthermic isolated limb perfusion. Nucl Med Commun, 2011. 32(9): p. 853-862.

Wierts R, Janssen MJ, Kingma H, Measuring saccade peak velocity using a low-frequency sampling rate of 50 Hz. IEEE Trans Biomed Eng, 2008. 55(12): p. 2840-2842.